Sunday, December 14, 2014

Bacteria: New antibiotics to prevent resistance – Business Week

Susanne Kutter

Whether in humans or animals: In Germany too much antibiotics are used, dangerous resistances arise. A German start-up wants to have discovered a new wonder weapon.

turkey, goose – or something completely different? Those who have not yet decided what he wants to eat as Christmas festive feast, should consider the well at least in the roast turkey. Because chances are that a good portion of medications the same lands with the animal on the plate.

The conclusion that can be at least one recent study by the State Agency for Nature , Environment and Consumer Protection in North Rhine-Westphalia: In 93 percent of all cases treated their breeder turkeys several times with up to ten different antibiotics – also with those which are meant for people and banned for poultry.

How to use antibiotics properly

  • As antibiotic resistance arising

    Bacteria are constantly changing to adapt to adapt changing environmental conditions. Small variations in the genome, the mutations that give some microbes a survival advantage, which then proliferate more than their other counterparts. This basic principle of evolution also helps pathogens to resist antibiotics, such as by destroying agents before they become dangerous to them. But we can make the germs harder to form this resistance, by observing some tactics.

  • Antibiotic use sparingly

    Even though it sounds trite – only when a bacterium comes into contact with an antibiotic resistance brings him a survival advantage. Therefore, physicians should only prescribe the means, if it is really necessary for medical reasons. But still they put a lot of antibiotics too lax and often. Even where they do not work: about the common cold. Most of which are caused by viruses against which each antibiotic is powerless. First rapid test for GPs has been around, the distinction between viruses or bacteria.

    In addition, farmers use broad-spectrum antibiotics for decades as mast agent in animal breeding, which is officially banned in Europe at least. Of the 2,000 per year spent in Germany, 350 tonnes tonnes for humans are determined, the rest for animals. In the stables caused by the constant contact with antibiotics quickly resistances, the skip on germs that infect humans.

  • Antibiotics correct dosage

    council, a doctor, an antibiotic, it may not be dosed too low or the treatment may be discontinued too early. Otherwise survive precisely those germs that have developed defense strategies. Enter the resistances
    then on to the offspring.

  • Carefully disinfect

    Hospitals are a kind of paradise for germs: The many occurring pathogens can exchange resistance genes; old, immunocompromised patients bring new germs into the house: Each operation opens the pathogens ideal approach paths in the body. Therefore, meticulous hygiene in hospitals is extremely important. Many homes sit there now from raising with germs patients about from poorly managed care homes, or send it consistently isolation.

  • Early diagnose

    So far, a doctor often does not know whether he is slammed with a broad-spectrum antibiotic early as quickly as possible to kill many types of bacteria, or whether he prefers to attack with a special means a single pathogen targeted
    . Gene rapid tests now make it possible to identify a pathogen before treatment accurately. So far lasted days

The problem:. The bacteria used to the agents, they are resistant , Then they attacked the people, there may be no salvation. Pneumonia is then rapidly fatal.

“As long as there are farming, farmers will use drugs,” says Markus Matushka of Greiffenclau. The scion of a noble family from the Rheingau believes with his 2009 established company Lysando to have found a way out of the dilemma with a whole new class of antibiotics that should not produce any dangerous drug resistance

The first customers in the. he has already convinced pharmaceutical industry. In summer, Boehringer Ingelheim Vetmedica secured a license to the new bacteria killers and she has since developed for use in animals on. And recently increased with the Siam Cement Group (SCG) in Thailand one of Asia’s largest industrial conglomerates with a 20 percent share in Lysando one.

  • Page 1: New antibiotics to prevent resistance
  • Page 2 Good germs in the body are spared

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